EyeCalc+ Ophthalmology Calculators

Plaquenil Retinal Tox

Risk assessment and screening recommendations for Hydroxychloroquine (Plaquenil) retinopathy.

References

• Melles RB, Marmor MF. The risk of toxic retinopathy in patients on long-term hydroxychloroquine therapy. JAMA Ophthalmol 2014.
• Marmor MF, Ahn SJ, Ehlers JP, Melles RB, Mieler WF, Sarraf D, Yusuf IH. Special AAO Report: Recommendations on Screening for Hydroxychloroquine Retinopathy (2025 Revision). Ophthalmology 2026.
• American Academy of Ophthalmology. Recommendations on Screening for Hydroxychloroquine Retinopathy - 2026 (AAO Clinical Statement). AAO Clinical Statement 2025.

This tool is for informational and educational purposes only and is not a substitute for professional medical judgment.